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Hanns Möhler Selected Research

taurolidine

10/2014Redox-directed cancer therapeutics: Taurolidine and Piperlongumine as broadly effective antineoplastic agents (review).
1/2007Pharmacokinetics of taurolidine following repeated intravenous infusions measured by HPLC-ESI-MS/MS of the derivatives taurultame and taurinamide in glioblastoma patients.
6/2005Induction of reactive oxygen intermediates-dependent programmed cell death in human malignant ex vivo glioma cells and inhibition of the vascular endothelial growth factor production by taurolidine.
3/2004Taurolidine-Fibrin-Sealant-Matrix using spray application for local treatment of brain tumors.
5/2003Enhancement of Fas-ligand-mediated programmed cell death by taurolidine.

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Hanns Möhler Research Topics

Disease

7Schizophrenia (Dementia Praecox)
01/2015 - 09/2002
5Anxiety Disorders (Anxiety Disorder)
01/2014 - 09/2002
4Epilepsy (Aura)
11/2004 - 08/2002
3Neoplasms (Cancer)
10/2014 - 03/2004
3Pain (Aches)
12/2009 - 01/2008
2Autism Spectrum Disorder
01/2015 - 01/2014
2Mental Disorders (Mental Disorder)
06/2011 - 01/2004
2Cognitive Dysfunction
12/2009 - 07/2008
2Glioma (Gliomas)
06/2005 - 05/2003
2Brain Neoplasms (Brain Tumor)
03/2004 - 05/2003
2Seizures (Absence Seizure)
09/2002 - 08/2002
1Postpartum Depression (Post-Natal Depression)
01/2019
1Fragile X Syndrome (Martin Bell Syndrome)
01/2018
1succinic semialdehyde dehydrogenase deficiency
01/2018
1Autistic Disorder (Autism)
01/2015
1Down Syndrome (Down's Syndrome)
01/2015
1Neurobehavioral Manifestations
01/2014
1Neuralgia (Stump Neuralgia)
08/2009
1Psychotic Disorders (Schizoaffective Disorder)
07/2008
1Chronic Pain
01/2008
1Glioblastoma (Glioblastoma Multiforme)
01/2007

Drug/Important Bio-Agent (IBA)

6gamma-Aminobutyric Acid (GABA)IBA
01/2015 - 09/2002
5taurolidineIBA
10/2014 - 05/2003
4GABA-A Receptors (GABA(A) Receptor)IBA
01/2015 - 07/2008
4Anti-Anxiety Agents (Anxiolytics)IBA
01/2015 - 09/2002
4Antineoplastic Agents (Antineoplastics)IBA
10/2014 - 05/2003
4Adenosine (Adenocard)FDA LinkGeneric
06/2009 - 08/2002
3Antidepressive Agents (Antidepressants)IBA
01/2019 - 01/2014
3Glycine Plasma Membrane Transport ProteinsIBA
05/2011 - 07/2008
2BenzodiazepinesIBA
01/2015 - 08/2009
2Analgesics (Analgesic Drugs)IBA
01/2015 - 01/2008
1brexanoloneIBA
01/2019
1NeurosteroidsIBA
01/2019
1Pregnanolone (Allopregnanolone)IBA
01/2019
1(3-aminopropyl)(n-butyl)phosphinic acidIBA
01/2018
1Acamprosate (Campral)FDA Link
01/2018
1Flumazenil (Romazicon)FDA LinkGeneric
01/2015
1piperlongumineIBA
10/2014
1Oxygen (Dioxygen)IBA
10/2014
1Diazepam Binding InhibitorIBA
06/2011
15-methoxy-methylindoleacetic acid (DBI)IBA
06/2011
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
05/2011
1Antipsychotic Agents (Antipsychotics)IBA
05/2011
1LigandsIBA
12/2009
1Glutamic Acid (Glutamate)FDA Link
06/2009
1L 838,417IBA
01/2008
1taurultamIBA
01/2007
1taurineamideIBA
01/2007
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2005
1Reactive Oxygen Species (Oxygen Radicals)IBA
06/2005
1Anticonvulsants (Antiepileptic Drugs)IBA
11/2004
1Fibrin Tissue Adhesive (Fibrin Sealant)IBA
03/2004
1Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
09/2002
1N-cyclopropyl adenosine-5'-carboxamide (CPCA)IBA
09/2002
1AcidsIBA
09/2002

Therapy/Procedure

4Therapeutics
10/2014 - 01/2007
2Drug Therapy (Chemotherapy)
03/2004 - 01/2004
1Intravenous Infusions
01/2007